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14-07-17

K4DD publishes a comprehensive overview article on Drug-Target binding kinetics  

In a true Public-Private effort, 9 K4DD partners have joined their knowledge and experience to establish a comprehensive overview article of drug Target-Binding Kinetics. The article published in Drug Discovery today can now freely be accessed using the following link.Read more

16-05-17

K4DD project results in first PhD thesis  

Binding interactions between neuropeptides (body’s neural signalling molecules), drugs and their target molecules were the focus of the first PhD thesis defense resulting from IMI’s K4DD project. Idira Nederpelt of Leiden University was the author of the thesis which already resulted in six peer-reviewed publications, with more to come. The thesis has helped expand the toolbox of...Read more

07-03-17

K4DD Scientific Meeting: "Binding kinetics: Time is of the essence"  

On 16-18 October, K4DD will organize an open scientific meeting. The meeting will be hosted by K4DD coordinator Bayer in Berlin, Germany.Read more

05-01-17

K4DD enters 2017 with the acceptance of another public private publication  

K4DD got off to a good start in 2017: we are happy to report the acceptance of another joint public-private research article (Hothersall et al., 2017). Looking back, 2016 was the most successful year so far for the project, with in total 16 K4DD publications. The project maintains it momentum in the new year and is determined to make 2017 - the final year of K4DD - an even bigger success. In...Read more

07-10-16

K4DD pharmacologists find new ways to predict the duration of drug effects  

The selection of new drug candidates can be improved by modeling drug-specific and disease-specific properties. This is the result of research done within the Kinetics of Drug Discovery (K4DD) project and has been published in Elseviers' Trends in Pharmacological Sciences. K4DD researchers from the Leiden University have presented a mathematical approximation to understand and visualize the...Read more

16-09-16

K4DD member organizes EFMC course  

K4DD members Ad IJzerman and Laura Heitman will be hosting an EFMC short course centered on drug-target binding kinetics. The, A matter of time: A kinetic perspective on drug-target interactions course will be organized in Leiden, The Netherlands on April 23-26, 2017. In this EFMC short course experts in the field will provide a firm conceptual framework for the study of target binding kinetics....Read more

07-07-16

K4DD publication highlights the case for partnership  

With a recent publication in the Journal of Medicinal Chemistry, the Kinetics for Drug Discovery consortium highlights the value of collaboration between public and private partners. Heptares and the Univeristy of Leiden, both K4DD partners, joined forces to investigate drug target binding kinetics of the human A2A adenosine receptor. The results of the public private partnership shed light on...Read more

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